Turk Kardiyol Dern Ars. 2019; 47(1): 4-9 | DOI: 10.5543/tkda.2018.82830
Safety of radial coronary angiography with uninterrupted direct-acting oral anticoagulant treatment
Tuğba Kemaloğlu Öz1
, Tayfun Gürol1
, Nedim Umutay Sarıgül2
, Utku Arslan1
, Maryam Kobegenova1
, Alper Aydın1
, Özer Soylu1
, Bahadir Dağdeviren11
Department of Cardiology, Bahçeşehir University Faculty of Medicine, İstanbul, Turkey2
Department of Cardiology, Kardio Bremen, Bremen, Germany
OBJECTIVE It is not known whether direct-acting oral anticoagulants (DOACs), such as dabigatran, apixaban, and rivaroxaban increase the risk of bleeding complications during or after coronary catheterization. The aim of this study was to investigate the safety of uninterrupted DOAC treatment during diagnostic radial coronary angiography (CAG).
METHODS This study included 160 patients who underwent diagnostic radial cardiac catheterization. The 60 patients in the group who were using a DOAC (apixaban, rivaroxaban, or dabigatran) were enrolled in a Group A. Post-procedure results from patients in Group A were compared with those of an age- and sex-matched control group (Group B) that included 100 patients who underwent radial CAG who did not use a DOAC.
RESULTS There was no significant difference in the procedure and compression times, creatinine level, or presence of hypertension, diabetes mellitus, smoking, alcohol use, vascular disease, or congestive heart failure between the 2 groups. During the 1 -month follow-up period, only 1 radial occlusion was registered in the control group (Group B). There was no case of a large hematoma (>5 cm or extending to the forearm), dissection, fistula, perforation, or compartment syndrome. Hematomas smaller than 5 cm were seen in 2 patients (1 in each group). No thrombotic events were observed during follow-up examinations.
CONCLUSION Performing radial CAG with uninterrupted DOAC treatment appears to carry no risk of increased early or short-term complications. The simple, uninterrupted DOAC strategy is comfortable, easy, and safe.
Anticoagulants, apixaban, coronary angiography; dabigatran; radial artery; rivaroxaban.
How to cite this article
Tuğba Kemaloğlu Öz, Tayfun Gürol, Nedim Umutay Sarıgül, Utku Arslan, Maryam Kobegenova, Alper Aydın, Özer Soylu, Bahadir Dağdeviren. Safety of radial coronary angiography with uninterrupted direct-acting oral anticoagulant treatment. Turk Kardiyol Dern Ars. 2019; 47(1): 4-9
Corresponding Author: Tuğba Kemaloğlu Öz, Türkiye