Relation of the Isolated Myocardial Muscle Bridge with Left Ventricular Hypertrophy and Left Ventricular Diastolic Dysfunction

Data concerning myocardial muscle bridge (MB) which causes s ignificant coronary constriction is limited and relationship between MB and left ventric ular diastolic function has not been investigated. The purpose of our study was to investigate the relationship between angiographically significant MB and left ventricular hypertrophy (L VH) and left ventric ular diastolic function (L VDF). Study population conıprised 38 pts (36 M, 2 F, nıea n age 53 ± 9.2) with MB associated with le ft ante rior descending artery cons triction (~60%) and without fixed atherosclerotic coronary lesion, and 40 age- and sexnıatched control cases (30 M, 10 F, mean age 52 ± 10.1) w ith normal coronary arteri o gram. Study g roup was evaluated by d igital coronary arteriography, and L VH (interventricular septunı (IVS) and posterior wall (PW) thickness, left ventricular mass index (L VMI) and L VDF ( mitral peak velocities of E and A waves, A/E> ı, isovolumetric re laxation time (IVRT) and E deceleration time (EDT) were determined by Mnıode, 2D and Doppler echocardiography. In pts w ith MB mean coronary constriction was 72± ı 2%, and frequency of LVH was significantly higher in pts with MB (n=l6, 42%) than CG (n=6, ı S %) (p