ISSN 1016-5169 | E-ISSN 1308-4488
Archives of the Turkish Society of Cardiology
Remember Diabetes Mellitus When Assessing Renal Blood Flow in Hypertensive Patients: A Renal Frame Count Study [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2023; 51(1): 32-39 | DOI: 10.5543/tkda.2022.77567

Remember Diabetes Mellitus When Assessing Renal Blood Flow in Hypertensive Patients: A Renal Frame Count Study

Idris Buğra Çerik1, Ferhat Dindaş2, Mehmet Birhan Yılmaz3
1Department of Cardiology, Faculty of Medicine, Cumhuriyet University, Sivas, Türkiye
2Department of Cardiology, Uşak Training and Research Hospital, Uşak, Türkiye
3Department of Cardiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Türkiye


BACKGROUND
Diabetes mellitus (DM) progresses with dynamic changes in renal blood flow and glomerular filtration. Renal frame count (RFC) is a cineangiographical parameter that is capable of presenting microvascular and macrovascular changes in the renal blood flow. We aimed to show the changes, which may be caused by DM in the perfusion, by using RFC.


METHODS
Totally 110 hypertensive subjects consisting of 55 DM patients and 55 non-DM patients as a control group who underwent renal angiography were retrospectively enrolled in the study. The RFC values of all subjects were calculated and compared to each other.


RESULTS
There were no significant differences between the two groups in terms of basal demographic characteristics and antihypertensive medications. The RFC value measured from the left renal artery was significantly lower in the DM group compared to the control group. (11.33±2.55, 13.49±3.24, respectively; p<0.001). The RFC value measured the right renal artery was detected to be significantly lower in the DM group than the control group (11.07±2.43, 13.33±3.07, respectively; p<0.001). The mean RFC value was also significantly lower in the DM group compared to the control group (11.20±2.18, 13.41±2.84, respectively;p<0.001). In the multivariable linear regression analysis conducted to determine the variables which may affect mean RFC, it was determined that only the HbA1C level had a relation with the mean RFC value.


CONCLUSION
To the best of our knowledge, this is the first study to show the influence of DM on RFC. RFC seems to decrease in DM subjects.

Keywords: Diabetes and prediabetes, renal blood flow, renal frame count

How to cite this article
Idris Buğra Çerik, Ferhat Dindaş, Mehmet Birhan Yılmaz. Remember Diabetes Mellitus When Assessing Renal Blood Flow in Hypertensive Patients: A Renal Frame Count Study. Turk Kardiyol Dern Ars. 2023; 51(1): 32-39

Corresponding Author: Idris Buğra Çerik, Türkiye
Manuscript Language: English


Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
per Paper:
0.22
SCImago Journal Rank: 0.348

Quick Search



Copyright © 2023 Archives of the Turkish Society of Cardiology