ISSN 1016-5169 | E-ISSN 1308-4488
Archives of the Turkish Society of Cardiology
The Association of Syntax and Mehran Scores with Inflammation in Patients with Contrast-Induced Nephropathy Secondary to Acute Coronary Syndrome [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. Ahead of Print: TKDA-76756 | DOI: 10.5543/tkda.2024.76756

The Association of Syntax and Mehran Scores with Inflammation in Patients with Contrast-Induced Nephropathy Secondary to Acute Coronary Syndrome

Sefa Erdi Ömür1, Emin Koyun2, Çağrı Zorlu1, Gülşen Genç Tapar1, Gökhan Cabri1
1Department of Cardiology, Tokat Gaziosmanpaşa University, Tokat, Türkiye
2Department of Cardiology, Sivas Numune Hospital, Sivas, Türkiye


OBJECTIVE
Contrast induced nephropathy (CIN) is the third most common cause of hospital-acquired acute renal failure. The increased use of contrast material in diagnostic and interventional cardiac catheterization procedures has made CIN a frequently encountered problem in clinical cardiology practice.The aim of our study is to understand the role of inflammatory biomarkers in patients developing CIN and to evaluate the relationship of inflammation with MEHRAN Score (MRS) and Syntax Score (SS).


METHOD
The study was conducted retrospectively and a total of 2161 patients who applied to the cardiology clinic with acute coronary syndrome [unstable angina (USAP), Non-ST-Elevation Myocardial Infarction (NSTEMI), ST-segment Elevation Myocardial Infarction (STEMI)] were included in the study. In the study, patients were divided into three groups: USAP(n: 477), NSTEMI(n: 612) and STEMI (n: 604). The relationship between Pan-immune Inflammation Value (PIV) and MRS and SS was evaluated.

Result: In patients developing CIN, in the intergroup (USAP, NSTEMI and STEMI) evaluation; PIV (1925.24[794.93-8412.79] vs 2178[1016.06-3273.56] vs 2262.97[1076.97- 4384.98] respectively), MRS (6.74±1.91 vs. 7.43±3.99 vs.7.6±3.08, respectively), SS (33.57±21.32 vs. 35.36±9.97 vs. 36.19±11.57 respectively) values were higher in the STEMI group than in the other two groups. A correlation was detected between PIV and MRS and SS in all groups.


CONCLUSION
PIV was found to be high in patients who developed CIN after acute coronary syndrome. PIV also correlated with Mehran score and SS. PIV can thus be a successful biomarker in the follow-up of CIN in this group of patients, as it is cheap and easy to study.

Keywords: Acute coronary syndrome, contrast induced nephropathy, mehran score, pan-immune ınflammation value, syntax score

How to cite this article


Corresponding Author: Sefa Erdi Ömür
Manuscript Language: English


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Journal Citation Indicator: 0.18
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