ISSN 1016-5169 | E-ISSN 1308-4488
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Transcatheter aortic valve implantation with the Edwards Sapien 3 valve: First experiences in Turkey [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2016; 44(8): 663-669 | DOI: 10.5543/tkda.2016.66168

Transcatheter aortic valve implantation with the Edwards Sapien 3 valve: First experiences in Turkey

Abdullah Nabi Aslan1, Serdal Baştuğ1, Hacı Ahmet Kasapkara2, Hüseyin Ayhan2, Hakan Süygün2, Telat Keleş2, Tahir Durmaz2, Nihal Akar Bayram2, Emine Bilen1, Engin Bozkurt2
1Atatürk Education And Research Hospital,department Of Cardiology,ankara,turkey
2Yıldırım Beyazıt University,faculty Of Medicine,department Of Cardiology,ankara,turkey


OBJECTIVE
Transcatheter aortic valve implantation (TAVI) has shown promising results in patients with severe aortic stenosis (AS) at high risk for open heart surgery. We aimed to evaluate outcomes of patients who underwent TAVI with Edwards SAPIEN 3 Transcatheter Heart Valve (S3), a second-generation TAVI device.

METHODS
Between November 2014 and June 2016, 31 high-risk patients received balloon-expandable S3 valve at Atatürk Training and Research Hospital that has the largest case series in Turkey.

RESULTS
Mean age of the patients was 76.1±12.6 years. Mean Society of Thoracic Surgeons and logistic European System for Cardiac Operative Risk Evaluation scores were 7.8%±3.1 and 31.4%±17.6, respectively. S3 valve was implanted in 27 patients via transfemoral approach and via trans-subclavian approach in 4 patients under local (n=29) or general (n=2) anesthesia. Procedural success rate was 100% (23 mm, n=7; 26 mm, n=16; 29 mm, n=8). Paravalvular aortic regurgitation (PAR) was absent or trivial in 29 (93.6%) patients and mild in 2 (6.4%) patients. Permanent pacemaker implantation (PPI) was required in 2 (6.4%) patients during the procedure, and in-hospital mortality occurred in 1 (3.2%) of those 2 patients.

CONCLUSION
S3 valve is associated with higher rate of device success and lower incidence of PAR, peripheral vascular complications, and need for new PPI.

Keywords: Aortic stenosis, Edwards Sapien 3 valve, permanent pacemaker, transcatheter aortic valve implantation.

Corresponding Author: Abdullah Nabi Aslan, Türkiye
Manuscript Language: English
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