ISSN 1016-5169 | E-ISSN 1308-4488
Early Atherosclerosis and Conduction Defect in a Rare Case of Dunnigan Type Familial Partial Lipodystrophy [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2024; 52(2): 138-142 | DOI: 10.5543/tkda.2023.35893

Early Atherosclerosis and Conduction Defect in a Rare Case of Dunnigan Type Familial Partial Lipodystrophy

Fatih Erkam Olgun, Ekrem Güler, Muhammed Furkan Çeleğen, Bora Demirçelik, Fethi Kılıçaslan, Bilal Boztosun
Department of Cardiology, Medipol University, Istanbul, Türkiye

A 45-year-old female patient was admitted to the emergency department with syncope. Her medical history revealed a diagnosis of Familial Partial Lipodystrophy 2 (FPLD2). The patient’s electrocardiogram showed a complete atrioventricular (A-V) block, and she had a history of insulin-dependent diabetes mellitus and coronary artery bypass surgery. A severe stenosis was observed in the aortic right coronary artery saphenous vein graft during coronary angiography, which was successfully revascularized. Subsequently, due to persistant syncope attacks, a permanent pacemaker was implanted after an electrophysiological study. This case highlights that serious cardiac conduction defects in patients with FPLD2 may not only be related to coronary artery disease but can also present as direct conduction defects.

Keywords: Conduction defect, early atherosclerosis, familial partial lipodystrophy

Corresponding Author: Muhammed Furkan Çeleğen, Türkiye
Manuscript Language: English
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