Archives of the Turkish Society of Cardiology
Distribution of Risk Variables and Global Risk Across Geographic Regions of Turkey [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2003; 31(6): 323-330

Distribution of Risk Variables and Global Risk Across Geographic Regions of Turkey

Altan Onat1, Bülent Uzunlar1, Gülay Hergenç1, Mehmet Yazıcı1, Hüseyin Uyarel1, Sadık Toprak1, Mehmet Özmay1, Vedat Sansoy1

Distribution of global coronary risk and of differences in the main risk factors in Turkey?s geographic regions were analyzed in a cross-sectional manner based on available data of the cohort of 2001/02. A point score that had been devised for the individual based on the Framingham and PROCAM risk scores and validated on the data of the Turkish Adult Risk Factor Study was used. Aside from major risk factors such as systolic blood pressure, total cholesterol and smoking status, HDL-cholesterol, waist circumference, C-reactive protein (CRP), fasting insulin, and prevalences of metabolic syndrome (MS) and coronary heart disease (CHD) were evaluated. Mean individual risk score in various regions varied between 15.7 and 17.7. The two regions with extreme risk scores corresponded to a difference of about 28-30% in absolute risk. The Marmara region demonstrated highest risk in both genders, while lowest risk was observed in Eastern Anatolia in men and the Black Sea region in women. Compared to the low risk category (<18 points in men, <21 points in women), individuals with high risk (?23 points in men, ?27 points in women) exhibited a 13-fold higher CHD likelihood. MS was observed with highest prevalence (48%) in the Mediterranean region, lowest in Eastern Anatolia (23%). Considering men and women combined, smoking was noted most in Central Anatolia, systolic pressure and total cholesterol levels in the Marmara region, whereas lowest HDL-cholesterol and highest CRP concentrations were noted in the Mediterranean region. It was concluded that, though differences in global coronary risk were modest across the regions, the Marmara region, followed by the Mediterranean region ranked highest. Main components of risk in the latter region were formed by those of insulin resistance, while risk appeared to originate chiefly from blood pressure and high LDL-cholesterol levels among residents of the Marmara region.

Keywords: Coronary heart disease, geographic regions, risk assessment, risk factors, Turkish adults

How to cite this article
Altan Onat, Bülent Uzunlar, Gülay Hergenç, Mehmet Yazıcı, Hüseyin Uyarel, Sadık Toprak, Mehmet Özmay, Vedat Sansoy. Distribution of Risk Variables and Global Risk Across Geographic Regions of Turkey. Turk Kardiyol Dern Ars. 2003; 31(6): 323-330
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