ISSN 1016-5169 | E-ISSN 1308-4488
Archives of the Turkish Society of Cardiology
Effect of Exercise on Left Atrium Mechanics in Mild Mitral Stenosis [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2024; 52(5): 315-321 | DOI: 10.5543/tkda.2024.26506

Effect of Exercise on Left Atrium Mechanics in Mild Mitral Stenosis

Müge Akbulut, Cansın Tulunay Kaya, Türkan Seda Tan, Demet Menekşe Gerede Uludağ, Çetin Erol
Department of Cardiology, Ankara University School of Medicine, Ankara, Türkiye


OBJECTIVE
A significant number of individuals with mild mitral stenosis (MS) experience exertional symptoms that are disproportionate to the hemodynamic severity of their condition. This study aims to determine whether exercise-induced left atrial (LA) dysfunction occurs in these patients and whether it is related to the development of symptoms.


METHODS
In this observational study, we recruited 46 patients with mild MS. Echocardiographic measurements were initially taken at rest, followed by a maximal exercise stress test. Patients were then returned to the echocardiography laboratory for post-exercise measurements.


RESULTS
Our study cohort exhibited considerably higher left atrial volume index (LAVI) values (mean: 40.52 ± 18.27) compared to those of a healthy population. Furthermore, the LA reservoir strain (mean: 17.1 ± 8.33) was reduced relative to reference values. Following exercise, there was no change in the LA reservoir strain. However, trans-mitral pressure gradients and systolic pulmonary artery pressures increased. The post-exercise mean trans-mitral gradient was identified as the sole predictor of symptom development in patients with mild MS.


CONCLUSION
The LA reservoir strain is already reduced in individuals with mild MS, and exercise does not lead to further decline in LA reservoir function in these cases. To our knowledge, this study is the first to explore the effects of exercise on LA mechanics in MS.

Keywords: Exercise stress test, left atrium strain, mitral stenosis

How to cite this article
Müge Akbulut, Cansın Tulunay Kaya, Türkan Seda Tan, Demet Menekşe Gerede Uludağ, Çetin Erol. Effect of Exercise on Left Atrium Mechanics in Mild Mitral Stenosis. Turk Kardiyol Dern Ars. 2024; 52(5): 315-321

Corresponding Author: Müge Akbulut
Manuscript Language: English


Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
per Paper:
0.22
SCImago Journal Rank: 0.348

Quick Search



Copyright © 2024 Archives of the Turkish Society of Cardiology



Kare Publishing is a subsidiary of Kare Media.