Turk Kardiyol Dern Ars. 2020; 48(4): 403-409 | DOI: 10.5543/tkda.2020.23793
The effect of transcatheter atrial septal defect closure on left heart function in pediatric patients
, Derya Aydın Şahin2
, Osman Başpınar3
, Murat Sucu41
Department of Pediatric Cardiology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey2
Department of Pediatric Cardiology, Mersin City Hospital, Mersin, Turkey3
Department of Pediatric Cardiology, Gaziantep University Faculty of Medicine, Gaziantep, Turkey4
Department of Cardiology, Gaziantep University Faculty of Medicine, Gaziantep, Turkey
OBJECTIVE The aim of this study was to use tissue Doppler imaging to evaluate the left atrial systolic and the left ventricular (LV) diastolic function as well as the left atrial ejection force in children who underwent transcatheter closure of a secundum atrial septal defect (ASD).
METHODS Tissue Doppler measurements of the left atrial ejection force, the mitral valve, and left atrial volume were performed before the ASD closure procedure, and on the 1st day, 10th day, and 1st and 3rd months after the procedure in 56 patients and in 28 healthy controls.
RESULTS There was a significant decrease in the septal and lateral a velocities on the first day (p<0.05). There was a statistically significant increase in the septal e/a parameters at the third month compared with the initial measurements. The left atrial ejection force was lower in patients with an ASD than in the healthy group (10.69±4.94 kdyn, 12.31±4.05 kdyn, respectively), but there was no significant difference (p=0.053). The left atrial ejection force was significantly greater in the patient group 3 months after the procedure, and there was no significant difference compared with the control group.
CONCLUSION Improvement in the LV diastolic and left atrial systolic functions was observed in children who underwent transcatheter closure of an ASD. There was no negative effect related to the devices used.
Left atrial ejection force, left atrial volume; secundum atrial septal defect; tissue Doppler; transcatheter closure.
How to cite this article
Ayşe Sülü, Derya Aydın Şahin, Osman Başpınar, Murat Sucu. The effect of transcatheter atrial septal defect closure on left heart function in pediatric patients. Turk Kardiyol Dern Ars. 2020; 48(4): 403-409
Corresponding Author: Ayşe Sülü, Türkiye