The Relationship Between PRECISE-DAPT Score and Spontaneous Reperfusion of Infarct-Related Artery in Patients with ST-Segment Elevation Myocardial Infarction

OBJECTIVE
The presence of spontaneous reperfusion (SR) and low PREdicting bleeding Complications In patients undergoing Stent implantation and subsEquent Dual Anti Platelet Therapy (PRECISE-DAPT) score in patients with acute coronary syndrome are associated with good clinical outcomes. This study aimed to investigate the relationship between SR and this score.
Materials and
METHODS
The study included 436 patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI). The presence of TIMI III blood flow in the infarct-related artery (IRA) before primary PCI was defined as SR. The patients were divided into 2 groups according to whether they had SR (n=49) or not (n=387). The PRECISE-DAPT score was calculated for each patient separately using the web-based calculator.

RESULTS
The frequency of hyperlipidemia was low, and the ejection fraction (EF) at admission was high in the group with SR. Glucose, troponin, creatine kinase-myocardial band (CK-MB) values, and PRECISE-DAPT score were higher in the group without SR. It was shown that the no-reflow phenomenon and high SYNTAX-I score were higher in the group without SR than in the group with SR. When multivariate regression analysis was performed, a high PRECISE-DAPT score was found to be an independent predictor of the absence of spontaneous reperfusion (odds ratio: 0,96 p=0,04).

CONCLUSION
The PRECISE-DAPT score is an independent predictor of the presence of spontaneous reperfusion in patients who experienced STEMI.