Archives of the Turkish Society of Cardiology
High fructose consumption may be associated with slow coronary flow [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2020; 48(7): 690-697 | DOI: 10.5543/tkda.2020.03205

High fructose consumption may be associated with slow coronary flow

Mevlüt Serdar Kuyumcu1, Aliye Kuyumcu2
1Department of Cardiology, Süleyman Demirel University Faculty of Medicine, Isparta, Turkey
2Department of Nutrition and Dietetics, Süleyman Demirel University Faculty of Health Sciences, Isparta, Turkey


OBJECTIVE
The precise pathophysiology of slow coronary flow (SCF) has not yet been clarified; however, many studies have shown that significant fructose consumption is associated with oxidative stress and inflammation, which may play a role in the pathophysiology of SCF. The aim of this study was to investigate the association between fructose consumption and isolated SCF.


METHODS
Patients with stable angina pectoris who underwent coronary angiography between December 2018 and April 2019 were evaluated for this study. In all, 45 patients with isolated SCF were selected as the patient group (SCF group) and 50 patients with a normal coronary flow pattern were enrolled as a control group. Participants used a dietary record to provide details of nutrient consumption and all of the data from the 2 groups were compared.


RESULTS
The high-sensitivity C-reactive protein (Hs-CRP) level (p=0.024), white blood cell count (p=0.038), and smoking rate (p=0.012) were higher in the SCF group. Total energy (p=0.029), carbohydrate (p=0.047), and fructose consumption (p<0.001) were also higher in the SCF group. Multivariable logistic regression analysis demonstrated that a higher level of Hs-CRP, fructose consumption, and smoking were independently associated with SCF.


CONCLUSION
The SCF group demonstrated a higher level of fructose consumption. Excessive fructose consumption may play a role in SCF pathophysiology

Keywords: Coronary artery disease, fructose; slow coronary flow.

How to cite this article
Mevlüt Serdar Kuyumcu, Aliye Kuyumcu. High fructose consumption may be associated with slow coronary flow. Turk Kardiyol Dern Ars. 2020; 48(7): 690-697

Corresponding Author: Mevlüt Serdar Kuyumcu, Türkiye
© Copyright 2020 Archives of the Turkish Society of Cardiology
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