Archives of the Turkish Society of Cardiology
Effect of overweight on cardiac function in children [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2013; 41(8): 714-723 | DOI: 10.5543/tkda.2013.02072

Effect of overweight on cardiac function in children

Şeref Alpsoy1, Aydın Akyüz1, Dursun Cayan Akkoyun1, Burçin Nalbantoğlu2, Birol Topçu3, Hasan Değirmenci1, Burcu Özdilek2, Mustafa Metin Donma2
1Namık Kemal University, Faculty Of Medicine, Department Of Cardiology
2Namık Kemal University, Faculty Of Medicine, Department Of Pediatrics
3Namık Kemal University, Faculty Of Medicine, Department Of Biostatistics


OBJECTIVES
It is known that obesity is related to heart failure. Asymptomatic left ventricular diastolic dysfunction (LVDD) is associated with the development of heart failure. The relationship between subclinical LVDD and overweight in children is not clear. The purpose of this study was to evaluate the effect of body mass index (BMI) and waist circumference on left ventricular mass index (LVMI) and LVDD in overweight children.

STUDY DESIGN
A total of 153 children were enrolled in the study. Of these, 91 were normal weight (age-adjusted BMI: 15-85 percentile), and 62 were overweight (age-adjusted BMI: 85-95 percentile). After measuring two-dimensional and M-mode echocardiographic variables, left and right ventricle diastolic functions were assessed by conventional and tissue Doppler imaging.

RESULTS
Compared to controls, overweight children had increased left atrium, aortic and left ventricular diameters, left ventricular wall thickness, LVM and LVMI, and septal mitral annulus e’, septal e’/a’, lateral e’, lateral e’/a’, lateral tricuspid annulus e’, and e’/a’ values. There were negative correlations between tissue Doppler diastolic parameters (septal mitral annulus e’, lateral mitral annulus e’, lateral tricuspid annulus e’, septal mitral annulus e’/a’, lateral mitral annulus e’/a’, and lateral tricuspid annulus e’/a’) and BMI, waist circumference, insulin, HOMA index, as well as systolic and diastolic blood pressure. Positive correlations were found between LVMI and BMI and between LVMI and waist circumference. BMI was found to be the predictor of decreased mitral anulus septal e’, septal e’/a’, lateral e’, lateral e’/a’.

CONCLUSION
Compared with normal-weight children, overweight children have decreased LV diastolic function. BMI is associated with a reduction in LV diastolic function in overweight children.

Keywords: Echocardiography, Doppler, adolescent, body mass index; nutrition surveys; child; diastole; obesity/epidemiology; Turkey; body weight.

How to cite this article
Şeref Alpsoy, Aydın Akyüz, Dursun Cayan Akkoyun, Burçin Nalbantoğlu, Birol Topçu, Hasan Değirmenci, Burcu Özdilek, Mustafa Metin Donma. Effect of overweight on cardiac function in children. Turk Kardiyol Dern Ars. 2013; 41(8): 714-723

Corresponding Author: Şeref Alpsoy, Türkiye
Manuscript Language: Turkish
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