Stabilization of Vulnerable Atherosclerotic Plaque

Acute coronary syndromes results mainly from rupture of a vulnerable atherosclerotic plaque. Regular exercising, quit to smoke, lipid lowering agents, angiatensin converting enzyme inhibitors have been shown to reduce the ineidence of acute coronary syndromes presumably through plaque stablization. The evidence supporting plaque stablization by these agents and the mechanisms by which these agents stablize plaques are discussed in this rev iew.