ISSN 1016-5169 | E-ISSN 1308-4488
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A Novel Electrocardiographic Marker to Predicting Total Mortality in Ischemic Stroke: Frontal QRS-T Angle [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. Ahead of Print: TKDA-71138 | DOI: 10.5543/tkda.2024.71138

A Novel Electrocardiographic Marker to Predicting Total Mortality in Ischemic Stroke: Frontal QRS-T Angle

Songül Usalp, Bayram Bağırtan
Department of Cardiology, Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul, Türkiye


OBJECTIVE
This study aimed to investigate the relationship between mortality and the frontal QRS-T angle (FQRS-TA), which has been obtained by calculating the absolute difference of QRS and T waves electrocardiographically (ECG), in patients diagnosed with ischemic stroke (IS).


METHODS
The research is a retrospective and cross-sectional study. The diagnosis of IS was confirmed from the brain images and physical examination. Patients with sinus rhythm were included in the study. FQRS-TA was measured by calculating the absolute difference between the QRS-axis and the T-axis automatically measured on the ECG. Patients were divided into two groups: those who died within 5 years and those who survived and were compared. P-values below 0.05 were considered significant.


RESULTS
A total of 322 IS were included in the study, 290 of whom lived and 32 died. Age, creatinine level, PR interval, QRS duration, cQT value, and FQRS-TA value (p < 0.05) were found higher in the death group.COX regression analyses were performed to examine the association between predictors of stroke-related mortality. Age [HR: 1.091, 95% (1.045-1.140), p<0.001], HDL [HR: 0.914, 95% (0.875-0.955), p<0.001] and FQRS-TA [OR: 1.011, 95% (1.003). -1.019) p=0.007] was associated with mortality. A FQRS-TA of 68 degrees or above was associated with cumulative mortality in the Kaplan-Meier survival analysis. (Log Rank [Mantel-Cox]: p=0.001).


CONCLUSION
In our study, we found that increased FQRS-TA was associated with mortality in IS patients.ECG parameters are simple and not time-consuming measurements and can provide important information about the patient's prognosis. According to our knowledge so far, this research is the first study on mortality in FQRS-TA and IS patients.

Keywords: Electrocardiography, frontal QRS-T angle, mortality, stroke

Corresponding Author: Songül Usalp, Türkiye
Manuscript Language: English
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