Clinical, Echocardiographic and Arrhythmogenic Features of Hypertensive Patients with Normal Coronary Arteries and Ischemia on Myocardial Perfusion Scintigraphy

Ischemic hypertensive patients with normal coronary arteries have been a research area for a long time. However studies have been intensively focused on the angiographic but not on elinical features of these patients. In this study we investigated clinical, echocardiographic and arrhythmogenic features of the patients depicted above. Fifty-four hypertensive patients (30 female, 24 male, mean age 57±9 years) who showed a revers ible perfu sion defect on scintigraphy but no significant angiographic stenosis wer e included in the study group. Eighty hypertensive patients (58 female, 22 male, mean age 57±1 O years) w ith normal myocardial perfusion scintigraphy served as a control group. After detailed histories were taken from the patients, physical exami n a tion , biochemi ca l a n a l ys is, echocardiographic examination and 12-lead ECG recording were performed. Arrhythmic events were investigated in 26 patients with and in 30 patients without perfusion defects using 24-hours Holter monitoring. When we assessed elinical and echocardiographic findings with logistic regression analysis, the factors related with the presence of myocardial perfusion defects were found as male gender, duration of high blood pressure, left ventricular end-diastolic dimension and mitral A wav e velocity in the who le study group (pKeywords: Scintigraphy, hypertension, echocardiography arrhythmia