ISSN 1016-5169 | E-ISSN 1308-4488
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Simultaneous total occlusion of two coronary arteries associated with use of drospirenone-ethinyl estradiol (oral contraceptive) [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2018; 46(1): 69-72 | DOI: 10.5543/tkda.2017.57606

Simultaneous total occlusion of two coronary arteries associated with use of drospirenone-ethinyl estradiol (oral contraceptive)

Hüsnü Atmaca1, Diyar Köprülü1, Tuncay Kiriş1, Gönül Zeren1, İrfan Şahin2
1Department of Cardiology, Ordu State Hospital, Ordu, Turkey
2Department of Cardiology, Bağcılar Training and Research Hospital, İstanbul, Turkey

Although the use of oral contraceptives is associated with an increased risk of venous thromboembolic disease, the risk of myocardial infarction (MI) is unclear. A new, third-generation contraceptive agent, drospirenone-ethinyl estradiol, which contains less estrogen and a new progestogen, drospirenone, in a different combination, has been considered more reliable in terms of risk of MI. However, there have been some cases of MI associated with the use of drospirenone-ethinyl estradiol, despite the protective effects of this oral contraceptive. In this report, a 33-year-old woman who had used drospirenone-ethinyl estradiol for 6 months was admitted with MI and symptoms of cardiogenic shock. Coronary angiography revealed the total occlusion of 2 coronary arteries and so percutaneous coronary intervention was performed. To the best of our knowledge, this is the first case report of simultaneous total occlusion of 2 coronary arteries associated with the use of drospirenone-ethinyl estradiol in the English-language medical literature.

Keywords: Cardiogenic shock, drospirenone-ethinyl estradiol; myocardial infarction; oral contraceptives.

Corresponding Author: İrfan Şahin, Türkiye
Manuscript Language: English
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