ISSN 1016-5169 | E-ISSN 1308-4488
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Remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patients [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2015; 43(3): 250-258 | DOI: 10.5543/tkda.2015.57106

Remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patients

Kevser Gülcihan Balcı1, Mustafa Mücahit Balcı1, Muhammed Murat Aksoy3, Samet Yılmaz1, Mehmet Aytürk4, Mehmet Doğan2, Ekrem Yeter2, Ramazan Akdemir3
1Turkiye Yuksek Ihtisas Research And Edücation Hospital, Cardiology Department, Ankara, Turkey
2Diskapi Yıldırım Beyazit Research And Edücation Hospital, Cardiology Department, Ankara, Turkey
3Sakarya University, Department of Cardiology,Sakarya,TURKEY
4Keciören Research And Edücation Hospital, Cardiology Department, Ankara, Turkey


OBJECTIVE
The aim of this study was to evaluate acute cardiac remodeling after transcatheter closure of atrial septal defect (ASD) in adult patients.

METHODS
This study included 19 patients (40.0±13.51 mean age) with secundum ASD who underwent successful transcatheter closure. All patients received routine transthoracic echocardiography, including tissue Doppler left ventricle (LV) and right ventricle (RV) myocardial performance indices (MPI), mitral annular plane systolic excursion (MAPSE) and tricuspid annular plane systolic excursion (TAPSE) before ASD closure, on first day, and at first and third months after closure.

RESULTS
Left ventricle end-diastolic diameter (LVEDD) increased (37±4 mm to 44±5 mm, p<0.001); RVEDD decreased markedly after closure (40±4 mm to 32±5 mm, p<0.001); and differences existed in LV and RV adaptation. While MAPSE (1.87±0.22 cm to 2.01±0.23 cm, p<0.001) and LVMPI improved soon after procedure (0.44±0.04 to 0.36±0.03, p<0.001), RVMPI worsened until the first month post-procedure (0.25±0.02 to 0.31±0.03, p<0.001), but recovered by the third month follow-up visit (0.31±0.03 to 0.27±0.02, p<0.001). TAPSE remained unchanged (2.49±0.46 cm to 2.51±0.32 cm, p=0.078).

CONCLUSION
Closure of ASD using the Amplatzer Septal Occluder device led to a decrease in RV size and an increase in LV size. In the early period, while LV function improved, RV function deteriorated, probably due to RV functional and anatomical differences.

Keywords: Atrial septal defect, echocardiography; left ventricle; right ventricle; ventricular remodeling

How to cite this article
Kevser Gülcihan Balcı, Mustafa Mücahit Balcı, Muhammed Murat Aksoy, Samet Yılmaz, Mehmet Aytürk, Mehmet Doğan, Ekrem Yeter, Ramazan Akdemir. Remodeling process in right and left ventricle after percutaneous atrial septal defect closure in adult patients. Turk Kardiyol Dern Ars. 2015; 43(3): 250-258

Corresponding Author: Mustafa Mücahit Balcı, Türkiye
Manuscript Language: English


Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
per Paper:
0.22
SCImago Journal Rank: 0.348

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