Turk Kardiyol Dern Ars. 2006; 34(1): 16-21

Diagnostic accuracy of multidetector computed tomography in patients with angiographically proven coronary artery disease

Alper Canbay¹, Nihal Akar¹, Tuğba Kayhan¹, Nihan Erdoğan², Deniz Şahin¹, Erdem Diker¹, Sinan Aydoğdu^1
1Ankara Numune Eğitim ve Araştırma Hastanesi Kardiyoloji Kliniği, Ankara
²Medmar Görüntüleme Merkezi, Ankara

OBJECTIVES
The success of multidetector computed tomography (MDCT) was assessed in detecting coronary artery stenoses in patients with angiographically proven coronary artery disease following acute myocardial infarction.

STUDY DESIGN
Eighteen patients (6 women, 12 men; mean age 51.3 years) who were hospitalized with the diagnosis of acute myocardial infarction undervvent coronary angiography after clinical stabilization was restored. Within two days of coronary angiography MDCT was performed. Segments that were angiographically shown to have stenosis exceeding 50% of the coronary artery lumen were evaluated by MDCT.

RESULTS
Of 288 segments studied, coronary angiography showed more than 50% stenosis in 48 segments, of which 24 segments (50%) were also demonstrated by MDCT (sensitivity 50%, specificity 97.5%). The success of MDCT according to the localization was as follovvs: nine in 10 proximal segments (sensitivity 90%, specificity 98.4%, positive predictive value 90%, negative predictive value 98.4%); seven in 12 middle segments (sensitivity 58.3, specificity 95.8%, positive predictive value 87.5%, negative predictive value 82.1%); and three in 14 distal segments (sensitivity 21.4, specificity 92.5%, positive predictive value 50%, negative predictive value 77.1%).

CONCLUSION
Multidetector computed tomography can be safely used as a noninvasive imaging method in the assessment of proximal and, in part, middle coronary artery segments.

Keywords: Coronary angiography/methods, coronary steno-sis/radiography; myocardial infarction; sensitivity and specificity; tomography, spiral computed/methods.

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