Serum Endothelin Levels in Myocardial Infarction [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 1995; 23(5): 375-379

Serum Endothelin Levels in Myocardial Infarction

Yesari KARTER0, Adnan YALDIRAN0, Gökhan DEMİR0, Fikret SİPAHİOĞLU0, Esin Olcay ÖZTÜRK0

We studied blood endothelin (ET-1) levels during the early phase of myocardial infarction and its relation to the progression of myocardial infarction. We determined serum ET-1 levels in 15 patients (4 females, 11 males) with a mean age of 52±11, with myocardial infarction proved by ECG findings and serum enzyme levels in the first 72 hours from the beginning of pain to find out the effect of ET-1 in the early phase of myocardial infarction. The control group consisted of 15 persons (8 females, 7 males) with a mean age of 42±16. ET-1 levels were studied in the venous sample with radioimmunoassay (Amersham Endothelin 1,2 (125 I) Assay System). ET-1 levels were significantly high in patients with myocardial infarction compared to the control group (p<0.05). The mean ET-1 level in the study group was 3.72±2.16 while it was 1.96±0.72 in the control group. We found a significant correlation with CK-MB, while there was none with lipid fractions, other biochemical values and ECG findings. The level of ET-1 increases in the early phase of myocardial infarction but whether it is the cause or the result should be further investigated.


How to cite this article
Yesari KARTER, Adnan YALDIRAN, Gökhan DEMİR, Fikret SİPAHİOĞLU, Esin Olcay ÖZTÜRK. Serum Endothelin Levels in Myocardial Infarction. Turk Kardiyol Dern Ars. 1995; 23(5): 375-379
Manuscript Language: Turkish
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