Telmisartan-Induced Myotoxicity İn Patients With Essential Hypertension

Drug-related muscular adverse effects are relatively common among some groups of drugs such as statins, and steroids. However, these adverse effects are not well known for angiotensin receptor blockers (ARBs). It is proposed that telmisartan and irbesartan may cause myotoxicity via an increased PPAR-gamma activity. Herein, we presented 2 hypertensive patients in whom telmisartan-induced myotoxicity was observed. Thus, physicians should remember that telmisartan and some other ARBs can also cause myopathy. Possible drug-drug interactions should be considered in case of concomitant prescription of these agents with other myopathic drugs.