Change of QT Dispersion in Patients with Coronary Artery Disease Undergoing Aneurysmectomy

The purpose of the study was to detect whether QT dispersion (QTD) was significantly different between patients with anterior myocardial infarction (MI) with and without left ventricular aneurysm and to evaluate the change of QTD after aneurysmectomy. For this purpose, 22 patients with anterior MI who underwent aneurysmectomy and coronary bypass surgery (Aneurysm Group: AG) and 15 patients with anterior MI but without aneurysm who had undergone coronary bypass surgery alone (Control Group: CG) were included in the study. QTD of patients were calculated from resting ECG recorded 1 day before and 1 month after the operation. Also heart-rate-corrected QT interval and QTD (QTcD) were calculated from Bazett's formula.
RESULTS
While preoperative QTcD were significantly higher in patients with left ventricular aneurysm (AG: 89±20 vs. CG: 76±19; p=0,04), postoperative QTcD was significantly lower in both groups compared to preoperative QTcD (AG: 89±20 vs. 70±25; p=0,001; CG: 76±19 vs. 61±22; p=0,02). However, the decrease of QTcD provided by operation between the groups, was not significantly different in patients with aneurysmectomy from those in the CG (19±28 - 14±18; p>0,05). Hence, QTD significantly increases in the presence of left ventricular aneurysm but aneurysmectomy does not provide additional reduction in QTD beyond that obtained from revascularization.