Mitral-Tricuspid Regurgitation Change After Transcatheter Aortic Valve Implantation-TAVI and Its Effect on Mortality and Hospitalization

OBJECTIVE
Moderate to severe mitral regurgitation (MR) and tricuspid regurgitation (TR) accompany approximately 20-60% of the patients who underwent transcatheter aortic valve implantation (TAVI). In this study, we aimed to evaluate the impact of TAVI on MR and TR, pulmonary hypertension, and reverse cardiac remodeling in patients who underwent TAVI.


METHOD
Seventy-nine patients who met the inclusion and exclusion criteria out of 240 patients who underwent TAVI were analyzed.


RESULTS
In our study, 46.8%(n=37) of the patients were male. Nineteen (24.1%) of the patients died within two years. There were 34(43%) patients with moderate-to-severe MR before TAVI, it decreased to 18(22.7%) after the procedure (p<0.05). Twenty-six patients had (32.9%) moderate-to-severe TR before TAVI, which decreased to 12(15%) after the procedure (p<0.05). While 50.6%(n=40) of the patients never admitted to the hospital after the procedure, 25, 12 and 2 patients were hospitalized one, twice and three times, respectively. Mean systolic pulmonary artery pressure (sPAP) values of the patients were 44.30±14.42mmHg and 39.09±11.77mmHg before and after the procedure, respectively (Z=-3.506, p<0.001). There was no correlation between MR and TR grade changes after TAVI and mortality and hospitalization needed during follow-up. There was also no statistically significant difference between tricuspid annular planar systolic excursion (TAPSE), lateral annular S' velocity, and left atrial volüme (LAV) index (LAVI), pre-and post-TAVI.


CONCLUSION
There was a significant decrease in moderate-to-severe MR and TR patients after TAVI, but this did not affect hospitalization and mortality. There was no significant difference in the right ventricular systolic functions and LAV and LAVI pre-and post-TAVI.