Anticardiolipin Antibodies in Acute Myocardial Infarction

A high anticardiolipin antibody (ACA) presence has been reported to be related to lupus anticoagulant positivity, venous and arterial thrombosis, thrombocytopenia and cerebrovascular events. This study was undertaken to determine whether there is any relation between ACA and thrombus formation in acute myocardial infaretion (AMI) patients. Patients with anterior or anteroseptal AMI were grouped according to 2-dimensional transthoracic echocardiography (TTE). Group I consisted to 22 patients (3 women, 19 men) with a mean age of 60.4 ± 12. 1, who had left ventricular thrombus (LVT) in TTE. Group II included ll patients (2 women, 9 men) w ith a me an age of 57.1 ± 8.6, w ithout L VT in TTE. A third group consisting of healthy individuals (1 woman, 9 men), with a mean age of 47.7 ± 4.4 were included in the study as controls. In all patients and healthy individuals routine blood b io cheın istry , activated partial thromboplastin time (APTT), ACA IgG, ACA IgM were determined after the TTE examination.
RESULTS
ACA IgG levels were 10.4 ± 11.5, 2.0 ± 3.3 and 2.3 ± 1.4 GPLU for groups, I, II and III, respectively, and were significantly higher in Group I compared with group II and III (p<0.02, pKeywords: Anticardiolipin , acute myocardial infarction, left ventricular thrombus .