Turk Kardiyol Dern Ars. 2005; 33(8): 476-479

Intensive antithrombotic treatment including tirofiban for intracoronary thrombosis in a patient with non-ST segment elevation acute myocardial infarction

Fatma Yiğit¹, Mustafa Kemal Batur², Göknur Tekin¹, Haldun Müderrisoğlu^1
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A 50-year-old male patient who presented with chest pain was hospitalized with a diagnosis of non-Q-wave myocardial infarction. Treatment with aspirin, clopidogrel, nitrates, beta-blocker, and heparin did not relive pain. Coronary angiography showed slow flow in the left anterior descending coronary artery and massive thrombotic occlusion in the septal artery. Tirofiban administration resulted in relief of chest pain. Control coronary angiography performed at 72 hours showed complete disappearance of the intracoronary thrombus, but slow flow in the left anterior descending coronary artery persisted. The patient was asymptomatic during a follow-up of three months.

Keywords: Angina, unstable; coronary angiography; coronary thrombosis/drug therapy; myocardial infarction; platelet glycoprotein GPIIb-IIIa complex/antagonists & inhibitors; tirofiban

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