Comparison of Mid-term Angiographic Results in Diabetic and Non- diabetic Patients After Coronary Artery Bypass Grafting

Diabetes mellitus is an established independent risk factor for significant morbidity and mortality for coronary artery bypass grafting. The impact of diabetes on bypass graft patency, development of new lesions and the rates of re-operation, re-intervention were assessed angiographically in 101 diabetic and 309 non-diabetic patients who had been operated between 1992-2001. The mean period of control angiography was 53.4 ±21.±2 vs 54.0 ±22.6 months. Compared with nondiabetic patients, the group with diabetes was older (61.3 ±10.7 years versus 59.4 ±11.2 years), comprised more women (26.7% versus 11.7% p=0,001), had more common triple-vessel disease (55.4 % versus 41.7%, p=0,02) and had lower ejection fractions (54.5 ±8.9 versus 56.6 ±8.5, p=0.03). A total of 309 (3.0 ±1.1) vs 902 (2.9 ±1.1) anastomosis was performed in 101 diabetic and 309 non-diabetic patients. The patency of left internal mammary artery -left anterior descending artery anastomosis were 95.9% vs 94.6% and 79.6% vs 73.7% in saphenous vein graft anastomosis. Development of new lesions were 37 (36.6 %) vs 79 (25.6% ), (p =0.041); reintervention rates were 33 (32.7%) vs 85 ( 27.5%)(p =0.3). The reoperation rate was 0 % vs 0.6% , in diabetic and non-diabetic patients, respectively. Freedom from reintervention and reoperation were 67.3% vs 72.7% (p=0.3) in group I and group II. Although diabetes appeared to be an independent risk factor for development of new lesions, no correlation was found on graft patency and in reinterventions between diabetics and non-diabetics.