Turk Kardiyol Dern Ars. 2025; 53(8): 607-614 | DOI: 10.5543/tkda.2025.98044
Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery Syndrome in Adults: A Case-Based Clinical Review
Almedina SpiljakInstitute for Healthcare of Transportation Employees Sarajevo, Bosnia and Herzegovina
This review provides a structured overview of ten published case reports of anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) syndrome in adults, with a focus on clinical presentation, diagnostic methods, and treatment approaches. A narrative review was conducted using the PubMed database to identify English-language case reports of adult patients with ALCAPA. Ten cases were selected based on clearly reported clinical features, diagnostic methods, and treatment approach. The most common symptoms included atrial fibrillation, chest pain, dyspnea, and syncope. Surgical correction was performed in four cases, while others were managed conservatively or with medical therapy. Adult-type ALCAPA presents with variable clinical manifestations and requires individualized treatment. Timely diagnosis and appropriate management are crucial for optimal outcomes.
Keywords: ALCAPA syndrome, congenital heart diseases, sudden cardiac death
Corresponding Author: Almedina Spiljak
Manuscript Language: English