Review Thrombolytic Therapy in Patients with Inferior Myocardial Infarction

Though mortality rate in patients with inferior MI is lower than that with anterior MI, thrombolytic therapy is beneficial to decrease the mortality rate in some situations in which a large are of myocardial tissue is jeopardized, namely in the following situations: Precordial ST depression, right ventricular infarction, hypotension, complete heart block. Additionaly, of the patient comes to the hospital very early (in 3 hours) or has a previous anterior MI and if ST segment elevations are seen in more than three ECG derivations, thrombolytic therapy can be given as it may be considered that a large myocardial region usually is in jeopardy. If here is no precordial ST depression, the benefit of thrombolytic therapy is not clear. Therefore, precordial ST depression can be accepted as a good marker to stratify the patients with inferior MI eligible for thrombolytic therapy. The benefit of reperfusion therapy is reduced in inferior MI with small infarct-related artery perfusion territory and that exhibiting no precordial ST depression.