Turk Kardiyol Dern Ars. 2013; 41(7): 638-641 | DOI: 10.5543/tkda.2013.63295

Heart failure after transvenous closure of atrial septal defect associated with atrial standstill and thiamine-responsive megaloblastic anemia

Vehbı Dogan¹, Filiz Şenocak², Utku Arman Örün², Özben Ceylan^2
1Department of Pediatric Cardiology, Gaziosmanpaşa University Faculty of Medicine, Tokat
²Department of Pediatric Cardiology, Dr. Sami Ulus Maternity And Children, Ankara

Despite advances in device closure for atrial septal defect, post-closure heart failure remains a clinical problem in adult patients but is seen only rarely in children. An eight-year-old boy, who had been followed by a local pediatrician with the diagnosis of diabetes mellitus and congenital heart disease, was consulted to us for cardiac re-evaluation. Electrocardiography demonstrated absent P waves, and echocardiography revealed enlargement of the right ventricle and both atria and secundum atrial septal defect. With the diagnosis of atrial standstill, secundum atrial septal defect and thiamine-responsive megaloblastic anemia, acute heart failure developed after transvenous closure of the atrial septal defect, which improved dramatically with thiamine and supportive treatment.

Keywords: Anemia, megaloblastic, atrial standstill; child; electrocardiography; heart failure/etiology; heart septal defects, atrial; thiamine.

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