Evaluation of Relationship Between Left Ventricular Hypertrophy and Diastolic Functions by New Echocardiographic Methods

The aim of this study was to investigate the relationship between left ventricular hypertrophy (LVH) and diastolic func tions by new echocardiographic methods. By this aim 35 (28 hypertensive, 7 normotensive) patients (19 M, 16 F, mean age± SD: 55.9 ± ı 1.7 years) w ith L VH who had left ventricle mass index (LVMI) > 134 g/m2 in men and > ı 10 g!m2 in women and angiographically proven to be free of significant coronary artery lesi o n s ( < 40 % stenosis) were studied. The mean (±SD) LVMI was ı58.4 ± 28.9 glm2. Using an Aloka SSD 2200 echocardiography device, mitral E and A velocities and time integrals (E and Avti), i sovoıumetri c relaxation time (IVRT), E deceleration time (EDT), A flow time (A-t), and pulmonary vein reversal flow time (PA-t) were measured in every patient. Lateral mitral annulus early and Iate diastolic velocities (Em, Am), Em deceleration time (EmDT), Am flow time (Am-t) were evaluated by tissue Doppler imaging. Color M-mode imagings of the mitral valve in apical 4-chamber view were obtained to ıneasure propagation velocity (Yp) and Yp acceleration time (Yp-at). No significant correlation w as fo und between L YMI and EDT, A-t, E/A, PA-t, and Aın-t (r=0.22, 0.23, - O.ı6, 0.28, and 0.31 , respectively). LYMI was weakly correlated with IYRT and Evti/Avti (r=0.45, -0.39, respectively) and had a good correlation with Em/Am, EınDT, Yp, and Yp-at (r= -0.66, 0.54, - 0.65, and 0.57 , respectively). Comparing the subgroups with and without hypertension, lower Em/Am, longer EınDT, lower Yp, and longer Yp-at were found in patients with hypertension. In evaluating of left ventricular diastolic functions, ıneasureınents obtained by tissue Doppler imaging and color M-ınode have better correlations with L YMI, coınpared to conventional ıneasureınents .