Neurologic outcome in patients with cardiac arrest complicating ST elevation myocardial infarction treated by mild therapeutic hypothermia:  The experience of a tertiary institution

Aruğaslan, Emre; Karaca, Mehmet; Özcan, Kazım Serhan; Zengin, Ahmet; Tatlısu, Mustafa Adem; Bozbeyoğlu, Emrah; Satılmış, Seçkin; Yıldırımtürk, Özlem; Yekeler, İbrahim; Nurkalem, Zekeriya

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Neurologic outcome in patients with cardiac arrest complicating ST elevation myocardial infarction treated by mild therapeutic hypothermia: The experience of a tertiary institution [Turk Kardiyol Dern Ars]

Turk Kardiyol Dern Ars. 2016; 44(2): 100-104 | DOI: 10.5543/tkda.2015.76436

Neurologic outcome in patients with cardiac arrest complicating ST elevation myocardial infarction treated by mild therapeutic hypothermia: The experience of a tertiary institution

Emre Aruğaslan¹, Mehmet Karaca¹, Kazım Serhan Özcan¹, Ahmet Zengin¹, Mustafa Adem Tatlısu¹, Emrah Bozbeyoğlu¹, Seçkin Satılmış¹, Özlem Yıldırımtürk¹, İbrahim Yekeler², Zekeriya Nurkalem³
¹Department Of Cardiology, Siyami Ersek Cardiovascular And Thoracic Surgery Center, Istanbul, Turkey
²Department Of Cardiovascular Surgery, Siyami Ersek Cardiovascular And Thoracic Surgery Center, Istanbul, Turkey
³Department of Cardiology, Istanbul Medipol University Faculty of Medicine, Istanbul, Turkey

OBJECTIVE
Therapeutic hypothermia improves neurologic prognosis after cardiac arrest. The aim of this study was to report clinical experience with intravascular method of cooling in patients with cardiac arrest resulting from ST-segment elevation myocardial infarction (STEMI).

METHODS
Thirteen patients (11 male, 2 famele; mean age was 39.6±9.4 years) who had undergone mild therapeutic hypothermia (MTH) by intravascular cooling after cardiac arrest due to STEMI were included. Clinical, demographic, and procedural data were analyzed. Neurologic outcome was assessed by Cerebral Performance Category (CPC) score.

RESULTS
Anterior STEMI was observed in 9 patients. One patient died of cardiogenic shock complicating STEMI. Mean cardiopulmonary resuscitation (CPR) duration and door-toinvasive cooling were 32.9±20.1 and 286.1±182.3 minutes, respectively. Precooling Glasgow Coma Scale score was 3 in 9 subjects. Twelve patients were discharged, 11 with CPC scores of 1 at 1-year follow-up. No major complication related to procedure was observed.

CONCLUSION
In comatose survivors of STEMI, therapeutic hypothermia by intravascular method is a feasible and safe treatment modality.

Keywords: Cardiac arrest, therapeutic hypothermia; myocardial infarction

Corresponding Author: Emre Aruğaslan, Türkiye
Manuscript Language: English

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