Turk Kardiyol Dern Ars. 1990; 18(2): 136-141
Orthotopic Heart Transplant in Turkey With 5 Months' Follow-Up
Ömer BAYEZİD1, Mehmet BALKANAY1, Mahmut CARİN1, İbrahim ÖZTEK1, Ahmet ÖCAL1, Ömer IŞIK1, Hüsnü SEZER1, Serdar ENER1, Çiğdem YAKUT1, Tuncer KOÇAK1, Selma SEZER1, Nuri ÇAĞLAR1, Mehmet ÖZDEMİR1, Cevat YAKUT1
A successful heart transplantation was performed at Koşuyolu Heart and Research Hospital, İstanbul, on September 7, 1989. Tnhe patient was a 58 year-old male. He had end-stage heart failure due to coronary artery disease with global ventricular dysfunction. Cardiac catheterization findings were consistent with the presence of ischemic cardiomyopathy and very poor ventricular function. The patient underwent orthotopic cardiac transplantation. Immunosuppression was based on cyclosporine, azathioprine and low dose steroid with an initial 3-day course of antithymocyte globulin. Three rejection episodes occurred within the first 6 weeks of transplantation and all were moderate. These episodes were treated with a course of intravenous methylprednisolone and ATG. The early function of the trnsplanted heart at 5 months has been satisfactory.
Keywords: Immunosuppression, cardiac transplantation, congestive heart failure
Manuscript Language: Turkish