Evaluation of Left Ventricular Functions by Doppler Echocardiography in Adolescents with Type 1 Diabetes Mellitus

Left ventricular diastolic and systolic functions (LVDF, LVSF) were investigated by Doppler echocardiography in 16 patients (9 male, 7 female, average 13.3±0.5 years) with type 1 diabetes mellitus (type 1 DM) and compared with a control group (CG) (10 male, 8 female, average 12.7±0.5 years). Compared to the CG, it was observed that among the LVDF parameters early diastolic mean and peak flow velocities (EVM, p<0.025, EVP, p<0.0005), E/A ratio (p<0.0005), and EVM integral (p<0.025) significantly decreased, acceleration (AAA, p<0.0005) and deceleration (ADA, p<0.005) averages of late diastolic flow increased, but LVSF parameters were not affected in patients with type 1 DM. In conclusion, diastolic left ventricular function was affected in our type 1 diabetic adolescent patients but not the systolic function.

Keywords: Doppler echocardiography, type 1 diabetes mellitus, diastolic, systolic function