A New Treatment Option for Hypertrophic Obstructive Cardiomyopathy: Alcohol-induced Septal Inrarction

The systolic approximation of the anterior leaflet of the mitral valve and hypertrophied, basal portion of the interventricular septum cause obstruction to the left ventricular outflow in hypertrophic obstructive cardiomyopathy. A new strategy for the management of hypertrophic obstructive cardiomyopathy was used in a 37-year-old female patient, resisıant to drug treatment with a mcan resting gradient of 22 mmHg. The first septal branch of left anterior descending artery was occluded w ith an injection of absolute alcohol. After induced septal infaretion the mean gradient in the left ventricular outflow was reduced to 3 mmHg. The functional class was reduced from III to I, and the basa! septal infaretion was documented by myocardial perfusion scintigraphy. This is the first published case in Turkey, who showed a very promising function al improvement.