Turk Kardiyol Dern Ars. 2005; 33(2): 115-125

The physiopathology and treatment of in-stent restenosis

Abdullah Doğan¹, Ömer Kozan², Nurullah Tüzün^1
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2

Percutaneous coronary intervention with stenting is an appropriate alternative to surgical revascularization in the management of coronary artery disease. Despite new medications and techniques, in-stent restenosis still remains an unresolved problem. Brachytherapy and drug-eluting stents are current therapeutic options to reduce in-stent restenosis and decrease the probability of its occurrence, respectively. This article revisits the pathophysiology and current therapeutic modalities of in-stent restenosis.

Keywords: Angioplasty, transluminal, percutaneous coronary; brachytherapy; coronary restenosis/physiopathology/therapy; drug implants; stents

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