Biventricular Pacing in Congestive Heart Failure

Biventricular pacing has recently been suggested as a therapeutic approach that has beneficial effects demonstrated in patients with advanced congestive heart failure and intraventricular conduction delay. It has been notified that the patients with significant QRS duration lengthening have more probability to benefit from this therapy. Although it has been demonstrated that symptomatic and left ventricular functional improvement can occur with biventricular pacing therapy, the effect on mortality has not been clarified yet. In this review, the results of biventricular pacing studies and the mechanisms of action of atrio-biventricular pacing have been discussed.