ISSN 1016-5169 | E-ISSN 1308-4488
pdf
Incidence, prevalence, and mortality estimates for chronic atrial fibrillation in Turkish adults [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2008; 36(4): 214-222

Incidence, prevalence, and mortality estimates for chronic atrial fibrillation in Turkish adults

Hüseyin Uyarel1, Altan Onat2, Hüsniye Yüksel3, Günay Can3, Serkan Ordu4, Dursun Dursunoğlu5
1Department of Cardiology, Siyami Ersek Cardiovascular and Thoracic Surgery Center, Istanbul, Turkey
2Turkish Society of Cardiology
3Department Of Cardiology And Public Health, Istanbul University Cerrahpasa School Of Medicine, Istanbul, Turkey
4Department Of Cardiology, Düzce University School Of Medicine, Düzce, Turkey
5Department Of Cardiology, Pamukkale University School Of Medicine, Denizli, Turkey


OBJECTIVES
We investigated the incidence, prevalence, and mortality of chronic atrial fibrillation (AF) in Turkish adults.

STUDY DESIGN
In a prospective and cross-sectional design, we analyzed 3,450 eligible participants (1707 men, 1743 women; mean age 52±13 years) of the Turkish Adult Risk Factor Study, who had been surveyed until 2006/07. Those who were dead and were found to have AF at baseline were excluded in the estimation of AF prevalence and incidence, respectively.

RESULTS
Atrial fibrillation was determined in 67 participants. The total follow-up was 34,100 person-years (mean 9.9 years). There were 43 prevalent and 46 incident cases, which corresponded to 1.25% and 1.35 per 1000 personyears, respectively. For age brackets of 32-59, 60-69, and ≥70 years, the prevalence rates were 0.46%, 2.09%, and 2.49%, and the incidence rates were 0.31, 1.98, and 3.50 per 1000 person-years, respectively. Both were higher in women of all age groups, with female-to-male ratios for overall prevalence and incidence being 1.69 and 1.19, respectively. Survival after onset of AF was 5 to 9 years and overall mortality was 6.8 per 100 person-years. Hypertension was the most common cause of AF, followed by advanced age. Contrary to expectations, waist circumference of men with AF was smaller by 1.9 cm than that of women. Serum C-reactive protein levels in men with AF (mean 1.21 mg/l) were significantly lower than women with AF (mean 2.62 mg/l) and than males without AF (mean 1.78 mg/l).

CONCLUSION
In Turkish adults, the current incidence and prevalence of chronic AF can be extrapolated to be 35,000 per year (22,000 in women) and 310,000 (200,000 in women), respectively. Considering the low incidence in males, it seems that inflammatory processes may play a minor role in the development of AF in Turkish men.

Keywords: Atrial fibrillation/epidemiology, cohort studies, incidence, prevalence; sex distribution; Turkey/epidemiology.

How to cite this article
Hüseyin Uyarel, Altan Onat, Hüsniye Yüksel, Günay Can, Serkan Ordu, Dursun Dursunoğlu. Incidence, prevalence, and mortality estimates for chronic atrial fibrillation in Turkish adults. Turk Kardiyol Dern Ars. 2008; 36(4): 214-222

Corresponding Author: Hüseyin Uyarel, Türkiye
Manuscript Language: Turkish


Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
per Paper:
0.22
SCImago Journal Rank: 0.348

Quick Search



Copyright © 2024 Archives of the Turkish Society of Cardiology



Kare Publishing is a subsidiary of Kare Media.