ISSN 1016-5169 | E-ISSN 1308-4488
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Long-term follow-up of 799 children with isolated ventricular septal defects [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2012; 40(1): 22-25 | DOI: 10.5543/tkda.2012.01679

Long-term follow-up of 799 children with isolated ventricular septal defects

Sevcan Erdem1, Nazan Özbarlas1, Osman Küçükosmanoğlu1, Hakan Poyrazoğlu2, Orhan Kemal Salih2
1Department of Pediatric Cardiology, Faculty of Medicine, Cukurova University, Adana, Turkey.
2Department of Cardiovascular Surgery, Faculty of Medicine, Cukurova University, Adana, Turkey.


OBJECTIVES
We evaluated long-term follow-up results and prognosis of pediatric patients with isolated ventricular septal defects (VSD).

STUDY DESIGN
The study included 799 patients (368 girls, 431 boys; mean age at diagnosis 24.3±37.4 months; median 6 months) who were monitored by the pediatric cardiology department for VSD. The mean follow-up period was 32.8±30.3 months (median 20 months).

RESULTS
The VSDs were classified as perimembranous (n=610, 76.4%), muscular (n=171, 21.4%), doubly committed subarterial (n=10, 1.3%), and multiple (n=8, 1%). Spontaneous closure rates were 42.7%, 13.1%, and 25% in muscular, perimembranous, and multiple VSDs, respectively, which corresponded to a mean age of 18.6±19.9 months (median 12 months) in muscular and 30.2±33.7 months (median 14.5 months) in perimembranous VSDs. Before 2 years of age, 78.1% of muscular and 58.6% of perimembranous VSDs underwent spontaneous closure. Of 256 defects (32%) that required surgical closure, 91.4% were of perimembranous location. The mean age at surgery was 38.8±49.1 months (median 11 months) for muscular, and 43.7±40.9 months (median 24 months) for perimembranous defects. During the follow-up period, the following complications were noted: aortic valve prolapse (0.7%), aortic regurgitation (0.6%), left ventricle-to-right atrium shunt (2.6%), subaortic ridge (3.7%), and infundibular stenosis (1.2%). Aortic regurgitation developed in eight patients (3.7%) after surgical closure.

CONCLUSION
Our data on the natural course and prognosis of VSDs may be of relevance with respect to patients’ age, defect type, and complications encountered in the follow-up period.

Keywords: Child, echocardiography, heart septal defects, ventricular/ surgery

How to cite this article
Sevcan Erdem, Nazan Özbarlas, Osman Küçükosmanoğlu, Hakan Poyrazoğlu, Orhan Kemal Salih. Long-term follow-up of 799 children with isolated ventricular septal defects. Turk Kardiyol Dern Ars. 2012; 40(1): 22-25

Corresponding Author: Sevcan Erdem, Türkiye
Manuscript Language: Turkish


Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
per Paper:
0.22
SCImago Journal Rank: 0.348

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