Archives of the
Turkish Society of Cardiology
Original Article - Interventional cardiology

Long pentraxin-3 measured at late phase associated with GRACE risk scores in patients with non-ST elevation acute coronary syndrome and coronary stenting

1.

Çanakkale Onsekiz Mart Üniversitesi Tıp Fakültesi, Kardiyoloji Anabilim Dalı, Çanakkale

2.

İzmir Üniversitesi, Kardiyoloji Anabilim Dalı, İzmir

3.

Central Hospital, Kardiyoloji, İzmir

4.

Kocaeli Üniversitesi Tıp Fakültesi, Mikrobiyoloji Ve Klinik Mikrobiyoloji Ana Bilim Dalı, Kocaeli

Archives of the Turkish Society of Cardiology 2012; 40: 205-212
DOI: 10.5543/tkda.2012.90083
Read: 286 Downloads: 90 Published: 01 July 2021

Objectives: We analyzed pentraxin 3 (PTX3) levels and the relation of PTX3 levels with GRACE risk scores in 39 patients with non-ST elevation acute coronary syndrome (ACS) and stabile angina after stenting.

Study design: Seventeen patients with ACS and 22 patients with stabile angina who underwent coronary stenting were included in the study. PTX3 levels were measured serially at admission, at the 8th hour and at the 24th hour after stenting.

Results: While diabetes and hypertension were more frequent in the stabile angina group, leukocyte counts were significantly higher in the ACS group. PTX3 levels measured at the 8th hour were significantly higher in the ACS group compared to the stabile angina group (p=0.003). Strong correlations were observed between 24th hour PTX3 levels and GRACE scores calculated for risk of death and death/MI at admission (in-hospital/to 6 months), and for risk of death/MI at discharge to 6 months (R=0.571, p=0.01, R=0.564, p=0.01; R=0.558, p=0.02, R=0.512, p=0.03; R=0.653, p=0.004, respectively).

Conclusion: The serum PTX3 levels may provide important information for the early risk stratification of patients with ACS who underwent coronary stenting.

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TURKISH
ISSN 1016-5169 EISSN 1308-4488