Archives of the Turkish Society of Cardiology
Effects of Iloprost and Sildenafil Citrate in A Patient with Pulmonary Hypertension Secondary to Histiocytosis X [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2002; 30(11): 722-725

Effects of Iloprost and Sildenafil Citrate in A Patient with Pulmonary Hypertension Secondary to Histiocytosis X

Taha OKAN1, Bahri AKDENİZ1, Ebru ÖZGÜN1, Özhan GÖLDELİ1, Atilla AKKOÇLU2
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Pulmonary hypertension secondary to pulmonary histiocytosis X is a progressive disease and has a poor prognosis. Despite conventional treatments (immunosuppresive agents, calcium channel blockers and continious O2 therapies) symptomatic improvement may not be seen. We found that single dose iloprost inhalation and oral sildenafil citrate treatment decreased pulmonary artery pressure in a patient with pulmonary hypertension secondary to histiocytosis X whose functional capacity was NYHA class IV. After one week of treatment period, functional capacity and six minutes walking test were improved with this combination. Combination of iloprost inhalation and oral sildenafil citrate might be an effective treatment options in pulmonary hypertension secondary to histiocytosis X.


How to cite this article
Taha OKAN, Bahri AKDENİZ, Ebru ÖZGÜN, Özhan GÖLDELİ, Atilla AKKOÇLU. Effects of Iloprost and Sildenafil Citrate in A Patient with Pulmonary Hypertension Secondary to Histiocytosis X. Turk Kardiyol Dern Ars. 2002; 30(11): 722-725
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