Turk Kardiyol Dern Ars. 2017; 45(5): 426-433 | DOI: 10.5543/tkda.2017.92837
Assessment of subclinical left ventricular systolic function using strain imaging in the follow-up of patients with chronic mitral regurgitation
, Ali Doğan1
, Saide Aytekin21
Department of Cardiology, İstanbul Bilim University Şişli Florence Nightingale Hospital, İstanbul, Turkey2
Department of Cardiology, İstanbul Florence Nightingale Hospital, İstanbul, Turkey
OBJECTIVE Determining optimal timing for surgery in asymptomatic mitral regurgitation (MR) remains a challenge. The aim of this study was to evaluate subclinical changes in left ventricular (LV) systolic functions using velocity vector imaging (VVI) during follow-up of patients with chronic mitral regurgitation (MR).
METHODS A total of 54 patients (mean age: 57.9±8 years; 55% male) with moderate-to-severe MR and normal LV ejection fraction (EF), and 30 healthy controls (mean age: 56±6.5 years; 55% male) were evaluated using conventional echocardiography and VVI at baseline.
RESULTS At the end of 12 months, measurements of 45 MR patients were repeated. There was no significant change in LV dimensions or EF on follow-up. LV peak systolic strain and strain rate (SR) were decreased in patients with MR compared with controls (strain: 16.29±3.30 to 23.4±1.9; p=0.0001 and SR: 0.93±0.39 to 4.9±0.6; p=0.0001) at baseline. Impairment was more significant on follow-up. (strain: 13.76±2.68 and SR: 0.27±0.14; p=0.0001).
CONCLUSION VVI-derived strain imaging might be used in the assessment of subclinical LV dysfunction and its progression during follow-up of patients with chronic MR especially in the decision of optimal timing for surgery.
Left ventricular functions, mitral regurgitation, strain.
Selen Yurdakul, Ali Doğan, Saide Aytekin. Assessment of subclinical left ventricular systolic function using strain imaging in the follow-up of patients with chronic mitral regurgitation. Turk Kardiyol Dern Ars. 2017; 45(5): 426-433
Corresponding Author: Saide Aytekin, Türkiye