Turk Kardiyol Dern Ars. Ahead of Print: TKDA-92428 | DOI: 10.5543/tkda.2019.92428
Reference pulse wave velocity values in a normotensive healthy Turkish population
Ankara Education And Research Hospital, Department Of Cardiology, Ankara, Turkey
OBJECTIVE Pulse wave velocity (PWV) is the main determiner of arterial stiffness. In daily practice, the normal range of the arterial stiffness is based on large multi-center studies conducted in the USA, Europe, Asia, and Australia. The goal of this study was to identify the reference values of brachial PWV in a healthy normotensive Turkish population with no cardiovascular risk factors.
METHODS This retrospective study involved healthy, adult Turkish public participants. Between September 2017 and January 2018, according to the inclusion criteria, 353 consecutive, normotensive individuals were enrolled in the study. Normal PWV and the 95% confidence interval values were acquired in all 353 subjects (mean age 55.03±15.38 years; range 2095 years), which were delineated into six age groups.
RESULTS The mean PWV was 7.75±1.89 m/s (range 4.2515.90 m/s). The PWV had a positive linear correlation with age (r2 = 0.94; 𝑃 = 0.00). In this cohort, the PWV increased gradually by an average of 59% with each decade of life until the age of 50 years, after which, the average PWV increased by 16%.
CONCLUSION To the best of our knowledge, this study is the first to define the reference values of PWV via brachial measure in a healthy normotensive Turkish population. Our data provide important information for daily clinical practice in Turkey.
Pulse wave velocity, aging process, arterial stiffness
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Corresponding Author: Alparslan Kilic, Türkiye