Archives of the Turkish Society of Cardiology
Long pentraxin-3 measured at late phase associated with GRACE risk scores in patients with non-ST elevation acute coronary syndrome and coronary stenting [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2012; 40(3): 205-212 | DOI: 10.5543/tkda.2012.90083

Long pentraxin-3 measured at late phase associated with GRACE risk scores in patients with non-ST elevation acute coronary syndrome and coronary stenting

Serkan Saygı1, Bahadır Kırılmaz1, İstemihan Tengiz2, Uğur Önsel Türk3, Hicran Yıldız1, Nurullah Tuzun3, Emin Alioğlu2, Gülden Sönmez Tamer4, Ertuğrul Ercan2
1Department of Cardiology, Canakkale Onsekiz Mart University, Medical Faculty, Canakkale, Turkey
2Department of Cardiology, Izmir University, Izmir, Turkey
3Department of Cardiology, Central Hospital, İzmir
4Department of Microbiology And Clinical Microbiology, Kocaeli University, Kocaeli, Turkey


OBJECTIVES
We analyzed pentraxin 3 (PTX3) levels and the relation of PTX3 levels with GRACE risk scores in 39 patients with non-ST elevation acute coronary syndrome (ACS) and stabile angina after stenting.

STUDY DESIGN
Seventeen patients with ACS and 22 patients with stabile angina who underwent coronary stenting were included in the study. PTX3 levels were measured serially at admission, at the 8th hour and at the 24th hour after stenting.

RESULTS
While diabetes and hypertension were more frequent in the stabile angina group, leukocyte counts were significantly higher in the ACS group. PTX3 levels measured at the 8th hour were significantly higher in the ACS group compared to the stabile angina group (p=0.003). Strong correlations were observed between 24th hour PTX3 levels and GRACE scores calculated for risk of death and death/MI at admission (in-hospital/to 6 months), and for risk of death/MI at discharge to 6 months (R=0.571, p=0.01, R=0.564, p=0.01; R=0.558, p=0.02, R=0.512, p=0.03; R=0.653, p=0.004, respectively).

CONCLUSION
The serum PTX3 levels may provide important information for the early risk stratification of patients with ACS who underwent coronary stenting.

Keywords: Acute coronary syndrome, angina pectoris, atherosclerosis C-reactive protein, GRACE risk score; myocardial infarction; pentraxin

How to cite this article
Serkan Saygı, Bahadır Kırılmaz, İstemihan Tengiz, Uğur Önsel Türk, Hicran Yıldız, Nurullah Tuzun, Emin Alioğlu, Gülden Sönmez Tamer, Ertuğrul Ercan. Long pentraxin-3 measured at late phase associated with GRACE risk scores in patients with non-ST elevation acute coronary syndrome and coronary stenting. Turk Kardiyol Dern Ars. 2012; 40(3): 205-212

Corresponding Author: Serkan Saygı, Türkiye
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