Archives of the Turkish Society of Cardiology
Pulmonary artery and right ventricle function in patients with bicuspid aortic valve [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2017; 45(3): 244-253 | DOI: 10.5543/tkda.2017.86060

Pulmonary artery and right ventricle function in patients with bicuspid aortic valve

Çetin Geçmen1, Gamze Babür Güler2, Suzan Hatipoğlu3, Muzaffer Kahyaoğlu1, Murat Çap1, Servet İzci1, Çağatay Önal1, Emrah Erdoğan1, Aykun Hakgör1, Özkan Candan1, Arzu Kalaycı1, Tuba Unkun1, İbrahim Akın İzgi1
1Kartal Kosuyolu Heart & Research Hospital,Cardiology,Istanbul
2Istanbul Medipol University,Cardiology,Istanbul
3Istanbul Emsey Hospital,Cardiology,Istanbul


OBJECTIVE
Bicuspid aortic valve (BAV) is a complex developmental anomaly caused by abnormal aortic leaflet formation during valvulogenesis. The present study is an assessment of the effects of BAV disease on the ascending aorta and pulmonary artery (PA), and an evaluation of the consequences for systolic and diastolic functioning of the left and right ventricles.


METHODS
Total of 66 patients were eligible for inclusion. Pulmonary artery maximum diameter (PAD) was obtained 1 cm distal to the pulmonary annulus. Using pulsed-wave tissue Doppler imaging, left ventricular (LV) early diastolic velocity (E′) measurement was obtained at the annulus with placement of sample volume. Right ventricle (RV) peak global strain rate during systole (RV-SRS), early diastole (RV-SRE), and late diastole (RV-SRA) were calculated.


RESULTS
In this study, 40.9% (n=27) of patients were female and average age was 35±11years. RV-SRS values (β=-.781, t=-2.723; p=0.010) and log-LV tissue Doppler imaging E’ (β=-2.996, t=-5.405; p=<0.001) were negatively correlated, and log-PAD (β=4.861, t=3.052; p=0.005) was positively and independently correlated with ascending aortic diameter.


CONCLUSION
Ascending aorta diameter is positively correlated with PA diameter in BAV patients, and RV strain rate and LV diastolic parameters are affected before development of the valve disease.

Keywords: Aortic valve, bicuspid, strain rate.

How to cite this article
Çetin Geçmen, Gamze Babür Güler, Suzan Hatipoğlu, Muzaffer Kahyaoğlu, Murat Çap, Servet İzci, Çağatay Önal, Emrah Erdoğan, Aykun Hakgör, Özkan Candan, Arzu Kalaycı, Tuba Unkun, İbrahim Akın İzgi. Pulmonary artery and right ventricle function in patients with bicuspid aortic valve. Turk Kardiyol Dern Ars. 2017; 45(3): 244-253

Corresponding Author: Muzaffer Kahyaoğlu, Türkiye
© Copyright 2019 Archives of the Turkish Society of Cardiology
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