Archives of the Turkish Society of Cardiology
Relation of neutrophil/lymphocyte ratio with the presence and severity of coronary artery ectasia [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2013; 41(3): 185-190 | DOI: 10.5543/tkda.2013.83030

Relation of neutrophil/lymphocyte ratio with the presence and severity of coronary artery ectasia

S. Selim Ayhan1, Serkan Öztürk1, Alim Erdem1, Mehmet Fatih Özlü1, Mehmet Özyaşar1, Kemalettin Erdem2, Mehmet Yazıcı1
1Department Of Cardiology, Abant Izzet Baysal University Faculty Of Medicine, Bolu, Turkey
2Department of Cardiovascular Surgery, Abant Izzet Baysal University Faculty Of Medicine, Bolu, Turkey


OBJECTIVES
It has been shown that the neutrophil to lymphocyte ratio (N/L ratio) is associated with cardiovascular events and mortality. In this study, we investigated the N/L ratio in patients with coronary artery ectasia (CAE).

STUDY DESIGN
Fifty patients diagnosed with CAE using coronary angiography were included in the study (29 male, 21 female; mean age, 51.1±7.1 years). The control group consisted of 28 patients who had normal coronary arteries as determined by coronary angiography (16 male, 12 female; mean age, 49.5±9.4 years). Basal characteristics were recorded. The number of ectatic segments was noted. Hematologic parameters were measured and the N/L ratio was calculated.

RESULTS
The N/L ratio was significantly higher in the CAE group compared with control group (median [25-75% percentile] 2.2 [1.6-3.0] vs. 1.8 [1.4-2.0], p=0.014, respectively). The Spearman correlation analysis demonstrated that the N/L ratio
positively correlated with number of ectatic segments (r=0.35; p<0.002). Multivariable logistic regression analysis showed an independent relationship between CAE and the N/L ratio (odds ratio 2.674, 95% confidence interval 1.184-6.039, p=0.018).

CONCLUSION
The N/L ratio is higher in patients with CAE. This ratio is related to presence and severity of CAE.

Keywords: Dilatation, pathologic/etiology, coronary aneurysm; coronary angiography; coronary vessels/pathology; lymphocyte count; neutrophils; risk assessment.

How to cite this article
S. Selim Ayhan, Serkan Öztürk, Alim Erdem, Mehmet Fatih Özlü, Mehmet Özyaşar, Kemalettin Erdem, Mehmet Yazıcı. Relation of neutrophil/lymphocyte ratio with the presence and severity of coronary artery ectasia. Turk Kardiyol Dern Ars. 2013; 41(3): 185-190

Corresponding Author: S. Selim Ayhan, Türkiye
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