Turk Kardiyol Dern Ars. Ahead of Print: TKDA-68792 | DOI: 10.5543/tkda.2018.68792
Predictors of in-hospital mortality in very very eldery patients presented with acute coronary syndrome; A single center study
, Mehmet Koray Adalı1
, Oğuz Kılıç1
, Ayşen Til2
, Yalın Tolga Yaylalı1
, Dursun Dursunoğlu1
, Havane Asuman Kaftan11
Cardiology Department,Pamukkale University Hospitals, Pamukkale/Denizli2
Public Health Department, Pamukkale University, Pamukkale/Denizli
Objective Acute coronary syndrome (ACS) becomes more frequent within elderly population, due to increased life expectancy. In this trial, our aim was to determine clinical and laboratory factors related to in-hospital mortality in patients over 80 years of age presented with ACS.Keywords:
Methods Total 171 patients over 80 years old and hospitalized due to the diagnosis of ACS were enrolled in this trial. Patients demographic, clinic features and laboratory data were screened from hospital data retrospectively.
Results During follow-up 19 of 171 patients (11.1%) died. There were more patients with ST-segment elevation myocardial infarction (STEMI) presentation in the death occured group [14 (73.7%) vs 31 (20.5%), p<0.001]. Patients who died during hospital follow-up had higher peak troponin [3.1 (7.2) ng/ml vs 0.3 (1.6) ng/ml, p<0.001] and CK-MB levels [96.7 (194) ng/ml vs 10.9 (36.2), p<0.001]. According to this; high GRACE risk score [OR: 1.074, 95% CI (1.039-1.110), p<0.001], ejection fraction ≤40% [OR: 8.113, 95% CI (1.101-59.773), p=0.040] and use of ACEI/ARB [OR: 0.075, 95% CI (0.006-0.995), p=0.049] were significantly associated with in-hospital mortality in patients presented with ACS over 80 years.
Conclusion Presentation with high GRACE risk score, not use of ACEI/ARB and low ejection fraction at admission were associated with in-hospital mortality in ACS patients over 80 years old.
Acute coronary syndrome, mortality, elderly
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Corresponding Author: Samet Yılmaz, Türkiye