Archives of the Turkish Society of Cardiology
Rate of blood pressure control and antihypertensive treatment approaches in diabetic patients with hypertension [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2014; 42(8): 733-740 | DOI: 10.5543/tkda.2014.53384

Rate of blood pressure control and antihypertensive treatment approaches in diabetic patients with hypertension

Nihan Kahya Eren1, Ece Harman2, Devrim Dolek2, Aliye Pelin Tütüncüoğlu2, Sadık Volkan Emren1, Fatih Levent1, Gülten Korkmaz3, Selcen Yakar Tülüce1, Cem Nazlı1
1Department of Cardiology, Izmir Katip Celebi University Ataturk Training and Research Hospital, Izmir
2Department of Endocrinology, Izmir Katip Celebi University Ataturk Training and Research Hospital, Izmir
3Department of Internal Medicine, Izmir Katip Celebi University Ataturk Training and Research Hospital, Izmir


OBJECTIVES
Hypertension is a common comorbidity in patients with type 2 diabetes. Management of hypertension is of paramount importance in reducing macro and microvascular complications of diabetes. The aim of this study is to determine the rate of blood pressure control (<140/85 mmHg) in diabetic patients with hypertension, and to evaluate the prescribing pattern of antihypertensive medications.

STUDY DESIGN
This was a prospective, cross-sectional, observational study conducted in a tertiary centre in Turkey. Of 707 patients with diabetes, 500 hypertensive patients were evaluated to determine control of hypertension and treatment attitudes. Logistic regression analysis was used to evaluate the likelihood of prescription of each class of antihypertensive medications for the presence of macro and microvascular complications.

RESULTS
Most of the patients (95%) were on antihypertensive therapy. Only 41% achieved target blood pressure values (<140/85 mmHg). Renin angiotensin system (RAS) blockers were the most frequently (82.4%) prescribed antihypertensive agents, and a combination of RAS blockers and diuretics were the most commonly preferred combination therapy. Most of the patients were on 1 antihypertensive drug or a combination of 2 drugs (39.5% and 44.7%, respectively). Patients with coronary artery disease were more likely to receive beta blockers (Odds ratio=3.6, 95% confidence interval=2.3-5.6; p<0.001).

CONCLUSION
Although most of the diabetic hypertensive patients were on hypertensive therapy, more than half had uncontrolled blood pressure.

Keywords: Antihypertensive agents, diabetes mellitus, hypertension/complications/drug therapy.

How to cite this article
Nihan Kahya Eren, Ece Harman, Devrim Dolek, Aliye Pelin Tütüncüoğlu, Sadık Volkan Emren, Fatih Levent, Gülten Korkmaz, Selcen Yakar Tülüce, Cem Nazlı. Rate of blood pressure control and antihypertensive treatment approaches in diabetic patients with hypertension. Turk Kardiyol Dern Ars. 2014; 42(8): 733-740

Corresponding Author: Nihan Kahya Eren, Türkiye
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