Turk Kardiyol Dern Ars. Ahead of Print: TKDA-49940 | DOI: 10.5543/tkda.2019.49940
The relationship between visible thrombus aspiration material with no-reflow and in-hospital mortality ratio in patients with anterior ST elevation myocardial infarction treated with primary percutaneous coronary intervention
, Caner Türkoğu2
, Oğuz Akkuş3
, Mustafa Gür11
Department of Cardiology, Health Sciences University, Adana Health Practice and Research Center, Adana, Turkey.2
Department of Cardiology, Malatya Training and Research Hospital, Malatya, Turkey.3
Department of Cardiolgy, Mustafa Kemal Univiersity, Hatay, Turkey.
The relationship between visible thrombus aspiration material with no-reflow and in-hospital mortality ratio in patients with anterior ST elevation myocardial infarction treated with primary percutaneous coronary intervention Keywords:
Running Head: Thrombus aspiration and no-reflow
OBJECTIVES Benefit of intracoronary thrombus aspiration (TA) during primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) is not fully clear yet. In this study we aim to investigate clinical impact of visible thrombus aspiration material.
METHODS We prospectively included 295 patients with TIMI 0 or I flow anterior STEMI. Manual TA devices were used for TA before PCI. The patients were divided into two group; visible thrombus aspiration group (VTA) and non-visible thrombus aspiration (non-VTA). No-reflow was defined as TIMI grade 0, 1 and 2 flows or TIMI grade 3 with myocardial blush grade 0 and 1. The primary end point was the occurrence of no-reflow.
RESULTS Visible thrombus aspiration was achieved 178 (60.3%) of patients. No- reflow was found significantly lower in VTA group (p< 0,001). Ejection fraction (EF) and ST-segment resolution were higher, and in-hospital mortality, Killip class II-IV and Post-pPCI TIMI frame count were lower in VTA group (p< 0.05 for all).
CONCLUSIONS Visible thrombus aspiration predicts lower rate of in hospital mortality and no-reflow in patients with anterior STEMI undergoing pPCI.
Key words: thrombus aspiration, no reflow, mortality, STEMI
thrombus aspiration, no reflow, mortality, STEMI
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Corresponding Author: Taner Şeker, Türkiye