Archives of the Turkish Society of Cardiology
Does a gender gap in secondary prevention from coronary artery disease exist in Turkish population? [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. Ahead of Print: TKDA-45392

Does a gender gap in secondary prevention from coronary artery disease exist in Turkish population?

Duygu Kocyigit1, Lale Tokgozoglu2, Meral Kayikcioglu3, Servet Altay4, Sinan Aydogdu5, Cem Barcin6, Cem Bostan7, Huseyin Altug Cakmak8, Alp Burak Catakoglu9, Samim Emet10, Oktay Ergene11, Ali Kemal Kalkan12, Baris Kaya2, Cansin Kaya13, Cihangir Kaymaz14, Nevrez Koylan15, Hakan Kultursay3, Aytekin Oguz16, Ebru Ozpelit17
1Cardiology Clinics, Afyonkarahisar Dinar State Hospital, Afyonkarahisar, Turkey.
2Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
3Department of Cardiology, Ege University Faculty of Medicine, Izmir, Turkey.
4Cardiology Clinics, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Center, Istanbul, Turkey.
5Cardiology Clinics, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey.
6Cardiology Clinics, Gulhane Training and Research Hospital, Ankara, Turkey.
7Department of Cardiology, Istanbul University Institute of Cardiology, Istanbul, Turkey.
8Department of Cardiology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey.
9Department of Cardiology, İstinye University Faculty of Medicine, İstanbul, Turkey
10Department of Cardiology, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey.
11Department of Cardiology, Izmir Kâtip Celebi University Ataturk Training and Research Hospital, Izmir, Turkey.
12Cardiology Clinics, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.
13Department of Cardiology, Ankara University Faculty of Medicine, Ankara, Turkey.
14Cardiology Clinics, Kartal Kosuyolu Yuksek Ihtisas Training and Research Hospital, Istanbul, Turkey.
15Cardiology Clinics, Gebze Anadolu Medical Center, Izmit, Turkey.
16Internal Medicine Clinics, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey.
17Department of Cardiology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.

Aims Women receive less preventive recommendations compared to men with similar risk profile, regarding pharmacological treatment, lifestyle modifications and cardiac rehabilitation. Herein, we aimed to investigate the impact of gender on cardiovascular risk profile and secondary prevention measures for CAD in Turkish population.
Methods Statistical analyses were based on the EUROASPIRE-IV(EA- IV) cross-sectional survey data obtained from 17 centers in Turkey. 18-80 years old males and females, hospitalized for a first or recurrent coronary event(CABG, PCI, AMI or acute myocardial ischemia) were eligible.
Results 88(19.7%) females and 358 males(80.3%) were included. At the time of index event, females were significantly older(p= 0.003) and undereducated(p<0.001). Non-smoking(p<0.001) and higher levels of depression and anxiety(both p<0.001) were more common in females. At the time of interview undertaken 6-36 months following the index event, central obesity(p< 0.001) and obesity (p= 0.004) were significantly more common in females. LDL-C, HDL-C or HbA1c levels did not significantly differ between genders. Fasting blood glucose was significantly higher(p= 0.003) and hypertension was more common in females(p= 0.001). Non-smoking was more common in females(p= 0.008). Increase in physical activity or weight loss after the index event did not differ between genders. There was no significant significance between genders regarding continuity of antiplatelets, statins, beta blockers or ACEi/ ARBs.
Conclusion Achievement of ideal body weight, fasting blood glucose and blood pressure targets was less in women despite similar reported medication use. This highlights the importance of implementation of lifestyle measures and adherence to medications especially in women.

Keywords: coronary artery disease, secondary prevention, cardiovascular risk factors, gender.

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Corresponding Author: Lale Tokgozoglu, Türkiye
© Copyright 2018 Archives of the Turkish Society of Cardiology
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