Turk Kardiyol Dern Ars. 2018; 46(4): 260-267 | DOI: 10.5543/tkda.2018.36151
The relationship between monocyte/high-density lipoprotein ratio and Selvester QRS score in patients with STEMI
, Mustafa Çetin, Serdar Türkmen, Hakan Taşolar, Erdal Aktürk
Department of Cardiology, Adıyaman University Training and Research Hospital, Adıyaman, Turkey
OBJECTIVE The ratio of monocytes to high-density lipoprotein (MHR) has recently been recommended as a new prognostic factor in cardiovascular disease. Studies have documented the value of the Selvester QRS score for prediction of prognosis of ST-elevation myocardial infarction (STEMI). However, no study has examined the association between the QRS score and MHR in patients with STEMI. The present study analyzed the relationship between MHR and QRS score in patients with STEMI.
METHODS A cohort of 99 consecutive patients who experienced STEMI between June and September 2016 was retrospectively evaluated. Serial electrocardiogram, monocyte count, and lipid panel measurements (day 1, day 2, and after discharge) were performed in all patients, and MHR was calculated. The patients were classified into 2 groups based on the median values according to the estimated infarct size: QRS score <6 and QRS score ≥6.
RESULTS The MHR was higher in the high QRS score group on day 1 in hospital (p=0.001). The MHR value was associated with QRS score in univariate logistic regression analysis and was found to be an independent predictor of the QRS score (Odds ratio: 0.390, 95% Confidence interval: 0.2520.605; p<0.001).
CONCLUSION A higher MHR serves as an indicator of inflammation and oxidative stress and was reported to be associated with a high QRS score. In addition, it was found to be an independent predictor of such scores during follow-up in patients with STEMI.
Ejection fraction, monocyte to HDL ratio; Selvester QRS score; ST-elevation myocardial infarction.
How to cite this article
Lütfü Aşkın, Mustafa Çetin, Serdar Türkmen, Hakan Taşolar, Erdal Aktürk. The relationship between monocyte/high-density lipoprotein ratio and Selvester QRS score in patients with STEMI. Turk Kardiyol Dern Ars. 2018; 46(4): 260-267
Corresponding Author: Lütfü Aşkın, Türkiye