Turk Kardiyol Dern Ars. Ahead of Print: TKDA-32967 | DOI: 10.5543/tkda.2018.32967
The Prospective Urban Rural Epidemiology (PURE) study: PURE TURKEY
, Özge Telci Çaklılı2
, Burcu Tümerdem Çalık31
Istanbul Medeniyet University Medical School, Department of Internal Medicine, Istanbul2
Kocaeli State Hospital, Internal Medicine Clinic, Kocaeli3
Marmara University Health Sciences Faculty, Department of Health Management, Istanbul
OBJECTIVE The Prospective Urban Rural Epidemiology (PURE) study is a prospective cohort study that collects data on social, environmental, and individual risk factors and chronic diseases among residents of 25 countries in the range of 35 to 70 years of age, living in rural and urban areas. The PURE study is directed by the Population Health Research Institute of McMaster University in Canada.
METHODS In Turkey, the study is being conducted in 8 cities. The initial fieldwork began in 2008. Questionnaires were completed, and anthropometric measurements, blood and urine samples, handgrip strength evaluations, electrocardiogram readings, and spirometer and body composition measurements were obtained. Each year, participants were followed up via telephone. Every third year, questionnaires, field measurements, and biological data sampling were repeated.
RESULTS PURE Turkey has 4056 participants (female: 60.7%, male: 39.3%; mean age: 50±9.1 years). Among them, 43.9% had metabolic syndrome and 52.8% were obese. Furthermore, 41.1% were hypertensive and 51.7% had a total cholesterol ≥200 mg/dL or were using a lipid-lowering agent. In patients with diabetes, 79.8% had low-density lipoprotein cholesterol levels ≥100 mg/dL. Although a dramatic change was not observed in those parameters in the follow-up years, the prevalence of diabetes mellitus increased from 13.7% in 2008 to 21% in 2015. The baseline and follow-up data of the PURE study were analyzed with the other countries participating in the study and reported for international publication.
CONCLUSION The PURE study is a large, ongoing, prospective epidemiological study that is investigating the causes of the causes of noncommunicable diseases in the world. In addition to revealing the health status of nations, the study also has the potential to affect health politics.
The Prospective Urban Rural Epidemiology, Turkey, Hypertension, Diabetes, Hyperlipidemia
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Corresponding Author: Aytekin Oğuz, Türkiye